Graphene oxide/silver nanoclusters based logic devices and their application to multiplexed analysis of miRNA Original Research Article Sensors and Actuators B: Chemical, Volume 273, 10 November 2018, Pages 408-417 Siqi Zhang, Wei Shi, Kai-Bin Li, Fengzao Chen, Jie Su, De-Man Han
Graphical abstractIn this work, we experimentally construct a series of multifunctional logic devices to perform nonarithmetic information processing and data transmission without the help of enzymes and label DNA. Moreover, by exploiting interactions between GO and DNA molecules and taking advantages of the extraordinarily high quenching efficiency of GO, we have developed a new platform to construct analog INHIBIT-OR logic gate which was utilized for distinguishing miR-21 and miR-141 from each other for the first time. The work integrates logic gate with biosensors, which has a great potential application in bioelectronic systems, intelligent detection and multivariate analysis.

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