Sensitivity enhancement of electrochemical biosensor via cobalt nanoflowers on graphene and protein conformational intermediate Original Research Article Journal of Electroanalytical Chemistry, Available online 11 June 2017, Pages Jianbo Liu, Minyan Zheng, Ping Zhang, Yonghui Shang, Jianbin Zheng, Wushuang Bai
Graphical abstractThe peak current of uHb/Co-GE/GCE is much greater than that of Hb/Co-GE/GCE, suggesting that the greater exposure of the electroactive center and the change of Hb conformation. The entrapped Hb in uHb/Co-GE/GCE is controlled to the most unfolding state, and the electrocatalytic ability of Hb/Co-GE/GCE is extremely improved.Image 1
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